Tepotinib

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Tepotinib

Tepotinib (pronounced te-po-ti-nib) is a type of medication used in the treatment of non-small cell lung cancer (NSCLC) that has spread to other parts of the body. It is specifically used for NSCLC that is caused by a defect in a gene called MET, which is also known as MET exon 14 skipping.

Etymology

The name "Tepotinib" is derived from the systematic International Union of Pure and Applied Chemistry (IUPAC) nomenclature. The "nib" suffix is common in many tyrosine kinase inhibitors, indicating its function as a protein kinase inhibitor.

Usage

Tepotinib works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells. It is taken orally, usually once a day, and is available in tablet form.

Side Effects

Common side effects of Tepotinib include fatigue, swelling in the hands or feet, nausea, and shortness of breath. More serious side effects can include liver problems and lung problems.

Related Terms

  • Non-small cell lung cancer: This is the most common type of lung cancer, and it spreads more slowly than small cell lung cancer.
  • Tyrosine kinase inhibitors: These are a type of medication that block certain proteins, such as tyrosine kinases, that can stimulate the growth of cancer cells.
  • MET exon 14 skipping: This is a genetic mutation that can lead to the development of non-small cell lung cancer. It is one of the specific conditions that Tepotinib is designed to treat.

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