Vinorelbine
Vinorelbine
Vinorelbine (pronounced: vee-nor-EL-been) is a type of chemotherapy drug used in the treatment of various types of cancer, including breast cancer and non-small cell lung cancer. It belongs to the class of drugs known as vinca alkaloids, which are derived from the periwinkle plant (Catharanthus roseus).
Etymology
The term "Vinorelbine" is derived from its chemical structure, which is similar to the natural alkaloid vinblastine, and its place of discovery, the French city of Villeurbanne. The "vin" in Vinorelbine stands for vinblastine, while "rel" is a reference to Villeurbanne.
Mechanism of Action
Vinorelbine works by interfering with the normal function of microtubules during cell division. This prevents the cancer cells from dividing and growing, thereby slowing or stopping the spread of the disease.
Side Effects
Common side effects of Vinorelbine include nausea, vomiting, constipation, and fatigue. More serious side effects can include neutropenia (a decrease in white blood cells), anemia (a decrease in red blood cells), and thrombocytopenia (a decrease in platelets).
Related Terms
- Chemotherapy
- Vinca alkaloids
- Vinblastine
- Catharanthus roseus
- Microtubule
- Cell division
- Neutropenia
- Anemia
- Thrombocytopenia
External links
- Medical encyclopedia article on Vinorelbine
- Wikipedia's article - Vinorelbine
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