Momelotinib
Momelotinib
Momelotinib (pronunciation: mo-mel-o-tin-ib) is a type of Janus kinase inhibitor used in the treatment of myelofibrosis, a rare type of bone marrow disease. The term "Momelotinib" is derived from the words "molecule" and "tyrosine kinase inhibitor", indicating its function as a molecule that inhibits the activity of tyrosine kinases.
Usage
Momelotinib is used to treat patients with myelofibrosis, a disease characterized by the abnormal growth of fibrous tissue in the bone marrow. This drug works by inhibiting the activity of Janus kinases, a type of enzyme that plays a crucial role in the signaling pathways that lead to the growth and development of cells.
Side Effects
Like all medications, Momelotinib can cause side effects. Some of the most common side effects include nausea, vomiting, diarrhea, and fatigue. More serious side effects can include anemia, thrombocytopenia, and neutropenia, which are conditions characterized by low levels of red blood cells, platelets, and neutrophils, respectively.
Related Terms
- Janus kinase inhibitor: A type of drug that blocks the activity of Janus kinases, enzymes that play a crucial role in cell growth and development.
- Myelofibrosis: A rare type of bone marrow disease characterized by the abnormal growth of fibrous tissue in the bone marrow.
- Bone marrow: The spongy tissue inside some of your bones, such as your hip and thigh bones. It contains immature cells, called stem cells.
- Anemia: A condition in which you lack enough healthy red blood cells to carry adequate oxygen to your body's tissues.
- Thrombocytopenia: A condition in which you have a low blood platelet count.
- Neutropenia: A condition characterized by a decrease in the number of neutrophils, a type of white blood cell that plays a crucial role in fighting off infections.
External links
- Medical encyclopedia article on Momelotinib
- Wikipedia's article - Momelotinib
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