Filgotinib
Filgotinib (pronounced as fil-go-ti-nib) is a Janus kinase inhibitor used in the treatment of rheumatoid arthritis and other autoimmune diseases.
Etymology
The name "Filgotinib" is derived from the name of the company that developed it, Galapagos NV, and the class of drugs it belongs to, known as Janus kinase inhibitors.
Pronunciation
The pronunciation of Filgotinib is "fil-go-ti-nib".
Medical Uses
Filgotinib is used in the treatment of moderate to severe rheumatoid arthritis in adults who have not responded well to one or more disease-modifying antirheumatic drugs (DMARDs). It is also being studied for its potential use in the treatment of other autoimmune diseases, including ulcerative colitis and Crohn's disease.
Mechanism of Action
Filgotinib works by inhibiting Janus kinase enzymes, which play a crucial role in the immune response. By blocking these enzymes, Filgotinib can help to reduce inflammation and slow the progression of autoimmune diseases.
Side Effects
Common side effects of Filgotinib include nausea, diarrhea, and upper respiratory tract infection. Serious side effects may include blood clots, cancer, and serious infections.
Related Terms
- Janus kinase inhibitor
- Rheumatoid arthritis
- Autoimmune diseases
- Disease-modifying antirheumatic drugs
- Ulcerative colitis
- Crohn's disease
External links
- Medical encyclopedia article on Filgotinib
- Wikipedia's article - Filgotinib
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