Epacadostat
Epacadostat
Epacadostat (pronounced as e-pa-ca-dos-tat) is a pharmaceutical drug that is primarily used in the treatment of cancer. It is an IDO1 (Indoleamine 2,3-dioxygenase 1) inhibitor, which means it works by blocking the activity of IDO1, an enzyme that plays a role in the immune system's response to cancer cells.
Etymology
The term "Epacadostat" is derived from the Greek words "epi" (meaning upon), "cad" (meaning to fall), and "stat" (meaning to stop). This is in reference to the drug's function of inhibiting the IDO1 enzyme, thereby 'stopping' the 'fall' (or progression) of cancer.
Usage
Epacadostat is used in combination with other immunotherapy drugs, such as pembrolizumab, to treat certain types of cancer, including melanoma, non-small cell lung cancer, and renal cell carcinoma. The combination of these drugs is believed to enhance the body's immune response against cancer cells.
Related Terms
- IDO1: An enzyme that plays a crucial role in the immune system's response to cancer cells. Epacadostat works by inhibiting the activity of this enzyme.
- Immunotherapy: A type of cancer treatment that uses the body's immune system to fight cancer cells. Epacadostat is often used in combination with other immunotherapy drugs.
- Pembrolizumab: An immunotherapy drug that is often used in combination with epacadostat to treat certain types of cancer.
- Melanoma: A type of skin cancer that can be treated with a combination of epacadostat and pembrolizumab.
- Non-small cell lung cancer: A type of lung cancer that can be treated with a combination of epacadostat and pembrolizumab.
- Renal cell carcinoma: A type of kidney cancer that can be treated with a combination of epacadostat and pembrolizumab.
External links
- Medical encyclopedia article on Epacadostat
- Wikipedia's article - Epacadostat
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