Epidermal growth factor receptor
| Epidermal growth factor receptor | |
|---|---|
| Term | Epidermal growth factor receptor |
| Short definition | epidermal growth factor receptor (eh-pih-DER-mul grothe FAK-ter reh-SEP-ter) A protein found on certain cell types that binds to a substance called epidermal growth factor. The epidermal growth factor receptor protein is involved in cell signaling pathways that control cell division and survival. |
| Type | Cancer terms |
| Specialty | Oncology |
| Language | English |
| Source | NCI |
| Comments | |
epidermal growth factor receptor - (pronounced) (eh-pih-DER-mul grothe FAK-ter reh-SEP-ter) A protein found on certain cell types that binds to a substance called epidermal growth factor. The epidermal growth factor receptor protein is involved in cell signaling pathways that control cell division and survival. Sometimes mutations (changes) in the EGFR gene cause epidermal growth factor receptor proteins to be produced in higher than normal amounts on some types of cancer cells. As a result, cancer cells divide faster. Drugs that block epidermal growth factor receptor proteins are used in the treatment of some types of cancer. Epidermal growth factor receptors are a type of receptor tyrosine kinase. Also called EGFR, ErbB1 and HER1
External links
- Medical encyclopedia article on Epidermal growth factor receptor
- Wikipedia's article - Epidermal growth factor receptor
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