Pexidartinib

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Pexidartinib

Pexidartinib (pronounced as pex-i-dar-ti-nib) is a medication used in the treatment of tenosynovial giant cell tumor (TGCT). It is a type of tyrosine kinase inhibitor that works by blocking certain proteins which help to keep the cells from growing.

Etymology

The name "Pexidartinib" is derived from the pharmaceutical naming convention, typically ending in "-tinib" for tyrosine kinase inhibitors.

Usage

Pexidartinib is used to treat adults with symptomatic tenosynovial giant cell tumor (TGCT) associated with severe morbidity or functional limitations, and not amenable to improvement with surgery. It is administered orally.

Side Effects

Common side effects of Pexidartinib include liver damage, hair color changes, increased cholesterol level, decreased neutrophil count, decreased lymphocyte count, eye edema, decreased hemoglobin, rash, dysgeusia, and decreased phosphate.

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