Pemphigoid: Difference between revisions
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{{SI}} | |||
{{Infobox medical condition | |||
| name = Pemphigoid | |||
| image = [[File:Legs_Bullous_Pemphigoid.jpg|alt=Legs with Bullous Pemphigoid]] | |||
| caption = Legs affected by Bullous Pemphigoid | |||
| field = [[Dermatology]] | |||
| symptoms = [[Blister]]s, [[itching]], [[skin]] [[rash]] | |||
| complications = [[Infection]], [[scarring]] | |||
| onset = Typically in older adults | |||
| duration = Chronic | |||
| causes = [[Autoimmune disease]] | |||
| risks = Age, [[genetic predisposition]], certain [[medications]] | |||
| diagnosis = [[Skin biopsy]], [[immunofluorescence]] | |||
| differential = [[Pemphigus]], [[dermatitis herpetiformis]], [[eczema]] | |||
| treatment = [[Corticosteroids]], [[immunosuppressants]] | |||
| medication = [[Prednisone]], [[azathioprine]], [[methotrexate]] | |||
| frequency = Rare | |||
}} | |||
[[File:Bullous_pemphigoid_new_image.jpg|Bullous Pemphigoid|thumb|left]] | |||
'''Pemphigoid''' is a group of rare [[autoimmune diseases]] that primarily affect the skin and mucous membranes. The condition is characterized by the formation of [[blister]]s, which can vary in size and may be filled with fluid. Pemphigoid is most common in older adults and can be life-threatening, particularly for those with poor general health. | '''Pemphigoid''' is a group of rare [[autoimmune diseases]] that primarily affect the skin and mucous membranes. The condition is characterized by the formation of [[blister]]s, which can vary in size and may be filled with fluid. Pemphigoid is most common in older adults and can be life-threatening, particularly for those with poor general health. | ||
==Types== | ==Types== | ||
There are several types of pemphigoid, including: | There are several types of pemphigoid, including: | ||
* '''[[Bullous Pemphigoid]]''': This is the most common type of pemphigoid. It is characterized by large, tense blisters that often appear on the skin areas that flex, such as the lower abdomen, upper thighs, and armpits. | * '''[[Bullous Pemphigoid]]''': This is the most common type of pemphigoid. It is characterized by large, tense blisters that often appear on the skin areas that flex, such as the lower abdomen, upper thighs, and armpits. | ||
* '''[[Mucous Membrane Pemphigoid]]''': This type of pemphigoid primarily affects the mucous membranes, such as the mouth, eyes, throat, and genitals. It can lead to scarring and, in severe cases, blindness. | * '''[[Mucous Membrane Pemphigoid]]''': This type of pemphigoid primarily affects the mucous membranes, such as the mouth, eyes, throat, and genitals. It can lead to scarring and, in severe cases, blindness. | ||
* '''[[Pemphigoid Gestationis]]''': This rare type of pemphigoid occurs during pregnancy, typically in the second or third trimester, and may also affect the newborn. | * '''[[Pemphigoid Gestationis]]''': This rare type of pemphigoid occurs during pregnancy, typically in the second or third trimester, and may also affect the newborn. | ||
==Causes== | ==Causes== | ||
Pemphigoid is caused by an abnormal immune response, where the body's [[immune system]] mistakenly attacks the cells in the skin or mucous membranes. The exact trigger for this immune response is unknown, but it may be linked to certain medications, UV light exposure, or other autoimmune diseases. | Pemphigoid is caused by an abnormal immune response, where the body's [[immune system]] mistakenly attacks the cells in the skin or mucous membranes. The exact trigger for this immune response is unknown, but it may be linked to certain medications, UV light exposure, or other autoimmune diseases. | ||
==Symptoms== | ==Symptoms== | ||
The primary symptom of pemphigoid is the formation of blisters on the skin or mucous membranes. Other symptoms may include itching, redness, and discomfort or pain in the affected areas. | The primary symptom of pemphigoid is the formation of blisters on the skin or mucous membranes. Other symptoms may include itching, redness, and discomfort or pain in the affected areas. | ||
==Diagnosis== | ==Diagnosis== | ||
Diagnosis of pemphigoid typically involves a physical examination, patient history, and specific diagnostic tests, such as a [[biopsy]] or [[blood test]] to detect specific antibodies. | Diagnosis of pemphigoid typically involves a physical examination, patient history, and specific diagnostic tests, such as a [[biopsy]] or [[blood test]] to detect specific antibodies. | ||
==Treatment== | ==Treatment== | ||
Treatment for pemphigoid aims to control symptoms and prevent complications. This may involve the use of [[corticosteroids]], [[immunosuppressant drugs]], and other medications to reduce inflammation and suppress the immune response. | Treatment for pemphigoid aims to control symptoms and prevent complications. This may involve the use of [[corticosteroids]], [[immunosuppressant drugs]], and other medications to reduce inflammation and suppress the immune response. | ||
==See also== | ==See also== | ||
* [[Autoimmune disease]] | * [[Autoimmune disease]] | ||
| Line 28: | Line 38: | ||
* [[Mucous Membrane Pemphigoid]] | * [[Mucous Membrane Pemphigoid]] | ||
* [[Pemphigoid Gestationis]] | * [[Pemphigoid Gestationis]] | ||
[[Category:Autoimmune diseases]] | [[Category:Autoimmune diseases]] | ||
[[Category:Dermatology]] | [[Category:Dermatology]] | ||
Latest revision as of 06:02, 6 April 2025
Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD's medical weight loss NYC, sleep center NYC
Philadelphia medical weight loss and Philadelphia sleep clinics
| Pemphigoid | |
|---|---|
| |
| Synonyms | N/A |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Blisters, itching, skin rash |
| Complications | Infection, scarring |
| Onset | Typically in older adults |
| Duration | Chronic |
| Types | N/A |
| Causes | Autoimmune disease |
| Risks | Age, genetic predisposition, certain medications |
| Diagnosis | Skin biopsy, immunofluorescence |
| Differential diagnosis | Pemphigus, dermatitis herpetiformis, eczema |
| Prevention | N/A |
| Treatment | Corticosteroids, immunosuppressants |
| Medication | Prednisone, azathioprine, methotrexate |
| Prognosis | N/A |
| Frequency | Rare |
| Deaths | N/A |
Pemphigoid is a group of rare autoimmune diseases that primarily affect the skin and mucous membranes. The condition is characterized by the formation of blisters, which can vary in size and may be filled with fluid. Pemphigoid is most common in older adults and can be life-threatening, particularly for those with poor general health.
Types[edit]
There are several types of pemphigoid, including:
- Bullous Pemphigoid: This is the most common type of pemphigoid. It is characterized by large, tense blisters that often appear on the skin areas that flex, such as the lower abdomen, upper thighs, and armpits.
- Mucous Membrane Pemphigoid: This type of pemphigoid primarily affects the mucous membranes, such as the mouth, eyes, throat, and genitals. It can lead to scarring and, in severe cases, blindness.
- Pemphigoid Gestationis: This rare type of pemphigoid occurs during pregnancy, typically in the second or third trimester, and may also affect the newborn.
Causes[edit]
Pemphigoid is caused by an abnormal immune response, where the body's immune system mistakenly attacks the cells in the skin or mucous membranes. The exact trigger for this immune response is unknown, but it may be linked to certain medications, UV light exposure, or other autoimmune diseases.
Symptoms[edit]
The primary symptom of pemphigoid is the formation of blisters on the skin or mucous membranes. Other symptoms may include itching, redness, and discomfort or pain in the affected areas.
Diagnosis[edit]
Diagnosis of pemphigoid typically involves a physical examination, patient history, and specific diagnostic tests, such as a biopsy or blood test to detect specific antibodies.
Treatment[edit]
Treatment for pemphigoid aims to control symptoms and prevent complications. This may involve the use of corticosteroids, immunosuppressant drugs, and other medications to reduce inflammation and suppress the immune response.
See also[edit]
| Hypersensitivity and autoimmune diseases (279.5–6) | ||||||||||||||||
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|
NIH genetic and rare disease info[edit]
Pemphigoid is a rare disease.
| Rare and genetic diseases | ||||||
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Rare diseases - Pemphigoid
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