Graham-Little syndrome
Graham-Little syndrome
Graham-Little syndrome (pronounced: grah-am lit-ul sin-drohm) is a rare condition characterized by alopecia, or hair loss, and lichen planopilaris, a type of skin inflammation. The syndrome was first described by the British dermatologist Henry Graham Little in 1915.
Etymology
The term "Graham-Little syndrome" is named after the British dermatologist Henry Graham Little, who first described the condition in 1915. The word "syndrome" comes from the Greek "syndromē," which means "concurrence of symptoms," or "running together."
Symptoms
The primary symptoms of Graham-Little syndrome include:
- Alopecia: This is a condition characterized by hair loss. In Graham-Little syndrome, the hair loss typically occurs on the scalp, eyebrows, and eyelashes.
- Lichen planopilaris: This is a type of skin inflammation that affects the hair follicles, leading to scarring and hair loss.
- Keratosis pilaris: This is a skin condition characterized by small, rough patches and tiny bumps, usually on the arms, thighs, cheeks, and buttocks.
Causes
The exact cause of Graham-Little syndrome is unknown. However, it is believed to be an autoimmune disorder, where the body's immune system mistakenly attacks its own cells. Some researchers suggest that it may be related to other autoimmune conditions, such as lupus and alopecia areata.
Treatment
Treatment for Graham-Little syndrome primarily focuses on managing the symptoms. This may include:
- Corticosteroids: These are medications that can help reduce inflammation and suppress the immune system.
- Immunosuppressants: These are drugs that can help reduce the body's immune response.
- Hair transplantation: In some cases, hair transplantation may be considered to help restore hair loss.
See also
External links
- Medical encyclopedia article on Graham-Little syndrome
- Wikipedia's article - Graham-Little syndrome
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