Dermatitis herpetiformis
Editor-In-Chief: Prab R Tumpati, MD
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| Dermatitis herpetiformis | |
|---|---|
| Synonyms | Duhring's disease |
| Pronounce | |
| Specialty | Dermatology, Gastroenterology |
| Symptoms | Itchy, blistering skin rash |
| Complications | N/A |
| Onset | Typically in adulthood |
| Duration | Chronic |
| Types | N/A |
| Causes | Gluten sensitivity |
| Risks | Celiac disease, Autoimmune disorders |
| Diagnosis | Skin biopsy, Direct immunofluorescence |
| Differential diagnosis | Eczema, Psoriasis, Scabies |
| Prevention | N/A |
| Treatment | Dapsone, Gluten-free diet |
| Medication | Dapsone |
| Prognosis | N/A |
| Frequency | Rare |
| Deaths | N/A |
Dermatitis herpetiformis (DH) is a chronic, blistering skin condition that is a form of celiac disease. The name "dermatitis herpetiformis" is a descriptive name and is not related to either dermatitis or herpes, but indicates that the rash is skin inflammation and is often grouped in clusters.
Symptoms
The primary symptom of dermatitis herpetiformis is an intensely itchy rash consisting of bumps and blisters. The rash usually appears on the elbows, knees, and buttocks. Most people with DH have the rash on the same parts of their body each time they have an outbreak.
Causes
Dermatitis herpetiformis is caused by a sensitivity or intolerance to gluten. Gluten is a protein found in wheat and grains. When a person with DH consumes foods or uses products that contain gluten, their immune system reacts by causing skin inflammation.
Diagnosis
Diagnosis of dermatitis herpetiformis is typically confirmed with a skin biopsy, which involves removing a small piece of skin to examine under a microscope. Blood tests may also be done to check for certain antibodies that are often present in people with DH.
Treatment
The main treatment for dermatitis herpetiformis is a lifelong gluten-free diet. Medications may also be used to help control the symptoms, but they are not a cure. Dapsone, a medication that suppresses the immune system, is commonly used.
Dermatitis_herpetiformis gallery
Close-up of dermatitis herpetiformis
Cross-reactivity hypothesis for the onset of dermatitis herpetiformis in patients with celiac disease
Micrograph of dermatitis herpetiformis
See also
References
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Contributors: Prab R. Tumpati, MD
