Goodpasture syndrome
Goodpasture syndrome (pronounced: good-pas-cher sin-drome) is a rare autoimmune disease in which antibodies attack the basement membrane in lungs and kidneys, leading to bleeding from the lungs and kidney failure. It is also known as Goodpasture's disease or anti-glomerular basement membrane disease.
Etymology
The syndrome is named after Dr. Ernest Goodpasture, an American pathologist, who first described it in 1919.
Symptoms
The symptoms of Goodpasture syndrome can vary greatly from person to person. Some people may experience only mild symptoms, while others may experience severe, life-threatening symptoms. Common symptoms include:
- Hemoptysis (coughing up blood)
- Dyspnea (shortness of breath)
- Hematuria (blood in the urine)
- Edema (swelling, usually in the legs)
- Fatigue (tiredness)
Causes
The exact cause of Goodpasture syndrome is unknown. However, it is believed to be an autoimmune disorder, which means that the body's immune system mistakenly attacks its own tissues. Some researchers believe that a viral or bacterial infection may trigger the immune response.
Diagnosis
Diagnosis of Goodpasture syndrome typically involves a combination of blood tests, urine tests, and a kidney biopsy. The blood tests look for the presence of anti-glomerular basement membrane antibodies, which are typically present in people with Goodpasture syndrome.
Treatment
Treatment for Goodpasture syndrome typically involves medications to suppress the immune system and reduce inflammation, as well as plasmapheresis, a procedure that removes the harmful antibodies from the blood.
Prognosis
With early diagnosis and treatment, the prognosis for people with Goodpasture syndrome can be quite good. However, if left untreated, the disease can lead to permanent kidney damage and can be life-threatening.
See also
External links
- Medical encyclopedia article on Goodpasture syndrome
- Wikipedia's article - Goodpasture syndrome
This WikiMD article is a stub. You can help make it a full article.
Languages: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
Urdu,
বাংলা,
తెలుగు,
தமிழ்,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
European
español,
Deutsch,
français,
русский,
português do Brasil,
Italian,
polski