Neutrophilic eccrine hidradenitis

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Neutrophilic Eccrine Hidradenitis

Neutrophilic eccrine hidradenitis (pronunciation: new-troh-fill-ik ek-reen hi-drad-uh-ni-tis) is a rare inflammatory skin condition that primarily affects the eccrine glands, which are a type of sweat gland found throughout the body.

Etymology

The term 'neutrophilic eccrine hidradenitis' is derived from the following components: 'neutrophilic' refers to the involvement of neutrophils, a type of white blood cell; 'eccrine' refers to the type of sweat gland affected; and 'hidradenitis' is derived from the Greek words 'hidros' (sweat) and 'aden' (gland), combined with the suffix '-itis', which denotes inflammation.

Symptoms

The condition is characterized by the sudden onset of painful, red or purple nodules or plaques on the skin, typically on the head, neck, and upper body. Other symptoms may include fever, malaise, and muscle pain.

Causes

Neutrophilic eccrine hidradenitis is often associated with systemic conditions such as leukemia and other hematologic malignancies, but it can also occur in healthy individuals. The exact cause is unknown, but it is thought to be related to the damage of eccrine sweat glands by neutrophils.

Diagnosis

Diagnosis is typically made based on the clinical presentation and histopathological examination of a skin biopsy, which shows neutrophilic infiltration of eccrine sweat glands.

Treatment

Treatment is primarily supportive and includes pain management and treatment of any underlying conditions. Topical or systemic corticosteroids may be used to reduce inflammation.

Related Terms

External links

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