Autoimmune polyendocrine syndrome

Autoimmune polyendocrine syndrome (pronounced: aw-toh-ih-MYOON pol-ee-END-oh-krin SIN-drohm), also known as APS, is a condition that affects the endocrine system. The endocrine system is a network of glands that produce and release hormones that help control many important body functions.

Etymology

The term "autoimmune polyendocrine syndrome" is derived from the following roots: "auto-" meaning self, "immune" referring to the immune system, "poly-" meaning many, and "endocrine" referring to the system of glands that secrete hormones directly into the circulatory system.

Types

There are three types of APS, each with different symptoms and associated conditions:

• Autoimmune polyendocrine syndrome type 1 (APS-1)
• Autoimmune polyendocrine syndrome type 2 (APS-2)
• Autoimmune polyendocrine syndrome type 3 (APS-3)

Symptoms

Symptoms of APS can vary widely depending on the specific glands that are affected. Common symptoms can include fatigue, weight loss, low blood pressure, and skin changes.

Causes

APS is caused by a problem with the immune system. Normally, the immune system protects the body from diseases and infections. In APS, the immune system mistakenly attacks the body's own tissues and organs.

Diagnosis

Diagnosis of APS is based on the presence of at least two endocrine deficiencies. Blood tests can be used to measure hormone levels and detect antibodies that are common in APS.

Treatment

Treatment for APS typically involves hormone replacement therapy to replace the hormones that the affected glands are no longer able to produce.

Related Terms

• Endocrine system
• Immune system
• Hormone
• Autoimmune disease
• Hormone replacement therapy

External links

• Medical encyclopedia article on Autoimmune polyendocrine syndrome
• Wikipedia's article - Autoimmune polyendocrine syndrome

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