Cutaneous small-vessel vasculitis

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Cutaneous Small-Vessel Vasculitis (pronunciation: kyu-tay-nee-us small-vessel vas-kyu-li-tis) is a medical condition that involves inflammation of the small blood vessels in the skin.

Etymology

The term "Cutaneous Small-Vessel Vasculitis" is derived from the Latin word "cutaneus" meaning skin, "small-vessel" referring to the small blood vessels, and "vasculitis" from the Latin "vasculum" meaning little vessel and "-itis" denoting inflammation.

Definition

Cutaneous Small-Vessel Vasculitis (CSVV) is a type of vasculitis that is confined to the small blood vessels in the skin. It is characterized by palpable purpura, which are small, raised, red or purple marks on the skin that do not blanch on applying pressure.

Symptoms

The primary symptom of CSVV is palpable purpura. Other symptoms may include urticaria, angioedema, and ulcers. In some cases, CSVV may also cause systemic symptoms such as fever, malaise, and arthralgia.

Causes

CSVV can be caused by various factors including infections, drugs, malignancies, and connective tissue diseases. However, in many cases, the exact cause remains unknown, and it is termed as idiopathic CSVV.

Diagnosis

The diagnosis of CSVV is primarily based on clinical features and skin biopsy. The biopsy typically shows leukocytoclastic vasculitis, which is the hallmark of CSVV.

Treatment

The treatment of CSVV primarily involves addressing the underlying cause, if known. Symptomatic treatment may include the use of nonsteroidal anti-inflammatory drugs (NSAIDs), corticosteroids, and other immunosuppressive agents.

See Also

External links

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