SAPHO syndrome

SAPHO Syndrome

SAPHO Syndrome (pronounced sah-foh) is a rare, chronic condition that involves the skin, bone, and joints. The acronym SAPHO stands for Synovitis, Acne, Pustulosis, Hyperostosis, and Osteitis.

Etymology

The term "SAPHO Syndrome" was coined in 1987 by Chamot et al. The acronym is derived from the major clinical features of the syndrome: Synovitis, Acne, Pustulosis, Hyperostosis, and Osteitis.

Definition

SAPHO Syndrome is a clinical condition where patients present with any combination of Synovitis (inflammation of the joints), Acne (a skin condition), Pustulosis (blistering skin diseases), Hyperostosis (excessive growth of bone), and Osteitis (inflammation of the bone).

Symptoms

The symptoms of SAPHO Syndrome can vary greatly from person to person. They may include skin lesions, joint pain, and bone abnormalities. The most common symptoms are skin and bone involvement, which can lead to chronic pain and physical disability.

Diagnosis

Diagnosis of SAPHO Syndrome is primarily based on clinical findings. There is no specific laboratory test for SAPHO Syndrome, but certain imaging studies such as X-rays, CT scans, and MRI can be helpful in confirming the diagnosis.

Treatment

Treatment for SAPHO Syndrome is aimed at managing symptoms and improving quality of life. This may include medications to reduce inflammation and pain, physical therapy, and in some cases, surgery.

Related Terms

• Synovitis
• Acne
• Pustulosis
• Hyperostosis
• Osteitis
• Chronic Pain
• Physical Disability

External links

• Medical encyclopedia article on SAPHO syndrome
• Wikipedia's article - SAPHO syndrome

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