Pemphigus vulgaris

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Pemphigus vulgaris (pronunciation: /pɛmˈfɪɡəs vʌlˈɡɛərɪs/) is a rare, chronic blistering skin condition caused by an autoimmune disorder.

Etymology

The term "Pemphigus" is derived from the Greek word "pemphix", meaning "bubble" or "blister". "Vulgaris" is Latin for "common".

Definition

Pemphigus vulgaris is characterized by the formation of blisters and erosions on the skin and mucous membranes. These blisters are often painful and may burst, leaving raw areas that can become infected.

Symptoms

The primary symptom of pemphigus vulgaris is the formation of soft, painful blisters on the skin and mucous membranes. Other symptoms may include mouth sores, skin rash, and itching.

Causes

Pemphigus vulgaris is caused by an autoimmune response, where the body's immune system mistakenly attacks healthy cells in the skin and mucous membranes. The exact cause of this autoimmune response is unknown.

Diagnosis

Diagnosis of pemphigus vulgaris is typically made through a combination of physical examination, patient history, and laboratory tests, including biopsy and immunofluorescence studies.

Treatment

Treatment for pemphigus vulgaris typically involves medications to suppress the immune system and manage symptoms. These may include corticosteroids, immunosuppressants, and antibiotics to treat or prevent infections.

Prognosis

With treatment, most people with pemphigus vulgaris can manage their symptoms and lead normal lives. However, the condition is chronic and requires ongoing management.

See also

External links

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