Histamine agonist
In the field of pharmacology, a histamine agonist is a specialized drug that amplifies the activity at one or more of the histamine receptor subtypes, essentially promoting the effects mediated by histamine.
Histamine Receptors and Their Agonists
Histamine receptors are proteins predominantly found on the surface of cells, and they interact with histamine to produce various physiological responses. These receptors are grouped into four subtypes:
- H1 Receptor: Primarily involved in allergic responses and the regulation of several neurotransmitters.
- H2 Receptor: Central in gastric acid secretion, especially in the stomach. Agonists such as Betazole and Impromidine are administered in diagnostic procedures to elevate histamine levels and study associated responses.
- H3 Receptor: Participates in the modulation of neurotransmitter release in the brain. Interestingly, Betahistine functions as a weak Histamine1 agonist but is a potent Histamine3 antagonist, leading to an increase in histamine levels in the body.
- H4 Receptor: Found mainly in bone marrow and white blood cells, playing a role in immune responses.
Therapeutic and Diagnostic Applications
Histamine agonists have a pivotal role in both therapeutic and diagnostic arenas:
- Their application can aid in comprehending the pathophysiology of diseases linked with histamine, like allergies or gastric disorders.
- They assist in determining the functionality of the histamine system and the corresponding physiological reactions.
See Also
- histamine antagonist: A compound that blocks the action of histamine by binding to one of its four receptors.
External Links
- Histamine+agonist at the US National Library of Medicine Medical Subject Headings (MeSH)
- An overview of histamine agonists in the Medical Subject Headings database.
- A comprehensive list of pharmaceutical agents related to histamine agonists.
 | |
|---|---|
 |
 |
| Pharmacomodulation | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Transform your life with W8MD's budget GLP-1 injections from $125.
W8MD offers a medical weight loss program to lose weight in Philadelphia. Our physician-supervised medical weight loss provides:
- Most insurances accepted or discounted self-pay rates. We will obtain insurance prior authorizations if needed.
- Generic GLP1 weight loss injections from $125 for the starting dose.
- Also offer prescription weight loss medications including Phentermine, Qsymia, Diethylpropion, Contrave etc.
NYC weight loss doctor appointments
Start your NYC weight loss journey today at our NYC medical weight loss and Philadelphia medical weight loss clinics.
- Call 718-946-5500 to lose weight in NYC or for medical weight loss in Philadelphia 215-676-2334.
- Tags:NYC medical weight loss, Philadelphia lose weight Zepbound NYC, Budget GLP1 weight loss injections, Wegovy Philadelphia, Wegovy NYC, Philadelphia medical weight loss, Brookly weight loss and Wegovy NYC
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
