Channel opener
Channel opener
Channel opener (pronunciation: /ˈtʃænəl ˈoʊpənər/) is a type of pharmacological agent that acts to open ion channels in the cell membrane.
Etymology
The term "channel opener" is derived from the English words "channel", referring to a pathway or conduit, and "opener", indicating something that opens or initiates. In the context of pharmacology, it refers to substances that open ion channels, allowing ions to pass through the cell membrane.
Function
Channel openers function by binding to specific sites on ion channels, causing a conformational change that opens the channel and allows ions to pass through. This can have various effects on the cell's function, depending on the type of ion channel and the ions involved. For example, potassium channel openers can help to regulate heart rate and blood pressure, while calcium channel openers can increase the influx of calcium ions into cells, affecting processes such as muscle contraction and neurotransmitter release.
Related Terms
- Ion channel: A protein structure in the cell membrane that allows ions to pass through.
- Potassium channel: A type of ion channel that selectively allows potassium ions to pass through.
- Calcium channel: A type of ion channel that selectively allows calcium ions to pass through.
- Pharmacological agent: A chemical substance used to treat, cure, prevent, or diagnose a disease or to promote well-being.
- Cell membrane: The semipermeable membrane surrounding the cytoplasm of a cell.
See Also
- Channel blocker: A type of pharmacological agent that acts to block ion channels, preventing ions from passing through.
- Ion channel modulator: A type of pharmacological agent that can either enhance or inhibit the function of ion channels.
External links
- Medical encyclopedia article on Channel opener
- Wikipedia's article - Channel opener
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