Reuptake inhibitor
Reuptake Inhibitor
A Reuptake Inhibitor (pronounced: ree-UHP-tayk in-HIH-bih-ter) is a type of drug that interferes with the reabsorption of neurotransmitters in the brain.
Etymology
The term "Reuptake Inhibitor" is derived from the English words "reuptake", meaning the reabsorption of a substance by the cell that originally produced and secreted it, and "inhibitor", which refers to a substance that slows down or prevents a particular chemical reaction or other process.
Function
Reuptake inhibitors work by blocking the transporter proteins that reabsorb neurotransmitters into the neuron after they have been released into the synaptic cleft. This increases the amount of neurotransmitter available in the synaptic cleft to bind to the receptor on the post-synaptic neuron, thereby enhancing or prolonging the neurotransmitter's effects.
Types
There are several types of reuptake inhibitors, including:
- Selective serotonin reuptake inhibitors (SSRIs)
- Serotonin-norepinephrine reuptake inhibitors (SNRIs)
- Norepinephrine-dopamine reuptake inhibitors (NDRIs)
- Tricyclic antidepressants (TCAs)
Each of these types of reuptake inhibitors targets different neurotransmitters.
Uses
Reuptake inhibitors are commonly used in the treatment of various mental health conditions, including depression, anxiety disorders, and attention deficit hyperactivity disorder (ADHD).
Side Effects
Like all drugs, reuptake inhibitors can have side effects. These can include nausea, insomnia, weight gain, and sexual dysfunction. It's important to discuss potential side effects with a healthcare provider before starting treatment.
See Also
External links
- Medical encyclopedia article on Reuptake inhibitor
- Wikipedia's article - Reuptake inhibitor
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