Metodesnitazene

From WikiMD's medical encyclopedia

Metodesnitazene


Metodesnitazene is a synthetic opioid that is part of the benzimidazole class of opioids. It was first synthesized in the 1960s as part of a series of analgesic agents. Metodesnitazene is an analog of Etonitazene, which is approximately 1000-1500 times more potent than morphine in animal models.

History

Metodesnitazene was first synthesized in the 1960s by a team of chemists at the pharmaceutical company Janssen Pharmaceutica. The team was led by Paul Janssen, who was searching for a new, more potent analgesic agent. Metodesnitazene was one of several benzimidazole opioids synthesized during this time, including Etonitazene and Clonitazene.

Pharmacology

Like other opioids, Metodesnitazene acts on the mu-opioid receptor in the brain to produce its analgesic effects. It is believed to be a full agonist at this receptor, meaning it can fully activate the receptor to produce its effects. The exact potency of Metodesnitazene in humans is not known, but it is believed to be significantly more potent than morphine.

Legal Status

Metodesnitazene is a controlled substance in many countries, including the United States, where it is classified as a Schedule I drug under the Controlled Substances Act. This means it has a high potential for abuse and no accepted medical use.

See Also

Opioid receptor modulators
μ-opioid
(MOR)
Agonists
(abridged;
full list)
* 3-HO-PCP
Antagonists
* (3S,4S)-Picenadol
δ-opioid
(DOR)
Agonists
* 3CS-nalmefene
Antagonists
κ-opioid
(KOR)
Agonists
* 3CS-nalmefene
Antagonists
Nociceptin
(NOP)




Controlled Substances
Legislation and Treaties
Agencies
Substance Schedules (US)
Related Topics
See also
This Controlled substances related article is a stub.


FlattenedRoundPills.jpg
This article is a stub related to pharmacology. You can help WikiMD by expanding it!


Navigation: Wellness - Encyclopedia - Health topics - Disease Index‏‎ - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes

Transform your life with W8MD's budget GLP-1 injections from $125.

W8mdlogo.png
W8MD weight loss doctors team

W8MD offers a medical weight loss program to lose weight in Philadelphia. Our physician-supervised medical weight loss provides:

NYC weight loss doctor appointments

Start your NYC weight loss journey today at our NYC medical weight loss and Philadelphia medical weight loss clinics.

Linkedin_Shiny_Icon Facebook_Shiny_Icon YouTube_icon_(2011-2013) Google plus


Advertise on WikiMD

WikiMD's Wellness Encyclopedia

Let Food Be Thy Medicine
Medicine Thy Food - Hippocrates

Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.

Retrieved from "https://wikimd.org/w/index.php?title=Metodesnitazene&oldid=5369438"

Contributors: Prab R. Tumpati, MD