Acetyldihydrocodeine
A semi-synthetic opioid analgesic
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Acetyldihydrocodeine is a semi-synthetic opioid analgesic that is derived from dihydrocodeine. It is used for the treatment of moderate to severe pain and is known for its effectiveness in pain management.
Pharmacology
Acetyldihydrocodeine is an opioid that acts primarily on the central nervous system to relieve pain. It binds to the opioid receptors, which are part of the G protein-coupled receptor family, and modulates the perception of pain. The drug is metabolized in the liver and excreted by the kidneys.
Medical uses
Acetyldihydrocodeine is prescribed for the relief of moderate to severe pain. It is often used in cases where other analgesics, such as nonsteroidal anti-inflammatory drugs (NSAIDs), are not effective. It may also be used in combination with other medications to enhance pain relief.
Side effects
Common side effects of acetyldihydrocodeine include nausea, vomiting, constipation, drowsiness, and dizziness. Like other opioids, it has the potential for addiction and abuse. Long-term use can lead to tolerance and physical dependence.
Legal status
The legal status of acetyldihydrocodeine varies by country. In some regions, it is classified as a controlled substance due to its potential for abuse and addiction. It is important for prescribers to adhere to local regulations when prescribing this medication.
Synthesis
Acetyldihydrocodeine is synthesized from dihydrocodeine through an acetylation process. This involves the introduction of an acetyl group to the dihydrocodeine molecule, enhancing its lipophilicity and potentially altering its pharmacokinetic properties.
Related pages
Gallery
Structural formula of Acetyldihydrocodeine
Ball-and-stick model of Acetyldihydrocodeine
Chemical structure of Acetyldihydrocodeine
Ball-and-stick model of Acetyldihydrocodeine
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