Mu-opioid receptor
Mu-opioid receptor
The mu-opioid receptor (pronounced: myoo-OH-pee-oid REE-sep-tor), also known as MOR, is a type of protein that is encoded by the OPRM1 gene in humans. It is a G protein-coupled receptor that interacts with the opioid class of drugs.
Etymology
The term "mu" is derived from the Greek letter μ, which is used in the International Union of Pure and Applied Chemistry (IUPAC) system to denote the third receptor type identified in the opioid receptor family. The term "opioid" comes from the Greek word "opion", meaning "poppy juice", referring to the natural source of these substances.
Function
The mu-opioid receptor is primarily responsible for the effects of opioids, including analgesia, euphoria, and respiratory depression. It is found in the central nervous system and the gastrointestinal tract, where it plays a key role in regulating pain and other physiological functions.
Related Terms
- Opioid receptor: A type of protein that opioids bind to in order to produce their effects.
- G protein-coupled receptor: A large family of receptors that respond to a variety of different signals.
- Analgesia: The inability to feel pain.
- Euphoria: A state of intense happiness and self-confidence.
- Respiratory depression: A state in which the rate and depth of breathing are reduced.
See Also
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