4',7-Dihydroxyflavone

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4',7-Dihydroxyflavone

Chemical structure of 4',7-Dihydroxyflavone

4',7-Dihydroxyflavone is a type of flavonoid, a class of plant secondary metabolites known for their diverse biological activities. This compound is characterized by the presence of two hydroxyl groups located at the 4' and 7 positions of the flavone backbone.

Chemical Structure

4',7-Dihydroxyflavone belongs to the flavone subclass of flavonoids, which are distinguished by a 15-carbon skeleton consisting of two phenyl rings (A and B) and a heterocyclic ring (C). The specific arrangement of hydroxyl groups in 4',7-Dihydroxyflavone contributes to its unique chemical properties and potential biological activities.

Biological Activity

Flavonoids, including 4',7-Dihydroxyflavone, are known for their antioxidant properties. They can scavenge free radicals and reduce oxidative stress, which is implicated in various chronic diseases. Additionally, flavonoids may exhibit anti-inflammatory, antimicrobial, and anticancer activities.

Antioxidant Properties

The antioxidant activity of 4',7-Dihydroxyflavone is primarily due to its ability to donate hydrogen atoms from its hydroxyl groups, neutralizing free radicals and preventing cellular damage.

Potential Health Benefits

Research into the health benefits of 4',7-Dihydroxyflavone is ongoing. It is being studied for its potential role in preventing or mitigating conditions such as cardiovascular disease, neurodegenerative disorders, and certain types of cancer.

Sources

4',7-Dihydroxyflavone can be found in various plant sources, particularly in those that are rich in flavonoids. These include certain fruits, vegetables, and herbs. The concentration of this compound can vary significantly depending on the plant species and environmental factors.

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Contributors: Prab R. Tumpati, MD