Dihydrocodeine

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Dihydrocodeine

Dihydrocodeine (/daɪˌhaɪdroʊkoʊˈdiːn/) is a semi-synthetic opioid analgesic prescribed for pain or severe dyspnea, or as an antitussive, either alone or compounded with paracetamol (as in co-dydramol) or aspirin. It was developed in Germany in 1908 and first marketed in 1911.

Etymology

The term "Dihydrocodeine" is derived from the Greek words "di" meaning "two", "hydro" meaning "water", and "codeine", a type of alkaloid found in opium. The "dihydro" prefix indicates that two hydrogen atoms have been added to the codeine molecule.

Pharmacology

Dihydrocodeine is twice as strong as codeine and has a slightly longer half-life. Like all opioids, dihydrocodeine works by binding to specific receptors in the brain and spinal cord, blocking the transmission of pain signals.

Side Effects

Common side effects of dihydrocodeine include dizziness, nausea, and constipation. More serious side effects may include respiratory depression and addiction.

Related Terms

  • Opioid: A class of drugs that includes the illegal drug heroin, synthetic opioids such as fentanyl, and pain relievers available legally by prescription, such as oxycodone, hydrocodone, codeine, morphine, and many others.
  • Codeine: A narcotic pain-reliever and cough suppressant similar to morphine and hydrocodone.
  • Paracetamol: Also known as acetaminophen, a common over-the-counter pain reliever and fever reducer.
  • Aspirin: A salicylate drug, often used as an analgesic to relieve minor aches and pains, as an antipyretic to reduce fever, and as an anti-inflammatory medication.

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