MCOPPB
Overview
MCOPPB is a chemical compound that acts as a potent and selective agonist for the GABAB receptor. It is primarily used in scientific research to study the function and pharmacology of GABAB receptors in the central nervous system.
Chemical Structure
MCOPPB is a synthetic compound with a complex chemical structure. The molecular formula of MCOPPB is C__H__N_O_, and it has a molecular weight of 340.37 g/mol. The structure includes a benzene ring, a pyridine moiety, and several functional groups that contribute to its activity as a GABAB receptor agonist.
Mechanism of Action
MCOPPB functions by binding to the GABAB receptor, a type of G protein-coupled receptor (GPCR) that is activated by the neurotransmitter gamma-aminobutyric acid (GABA). Upon binding, MCOPPB mimics the action of GABA, leading to the activation of the receptor and subsequent downstream signaling pathways. This results in the modulation of neurotransmitter release and neuronal excitability.
Pharmacological Effects
The activation of GABAB receptors by MCOPPB can lead to various physiological effects, including:
- Inhibition of neurotransmitter release
- Reduction in neuronal excitability
- Modulation of synaptic plasticity
These effects make MCOPPB a valuable tool in neuroscience research, particularly in studies investigating the role of GABAB receptors in neurological disorders such as epilepsy, anxiety, and depression.
Research Applications
MCOPPB is used extensively in laboratory settings to:
- Investigate the pharmacodynamics and pharmacokinetics of GABAB receptor agonists
- Explore the therapeutic potential of GABAB receptor modulation in various disease models
- Study the physiological and behavioral effects of GABAB receptor activation in animal models
Safety and Handling
As with many research chemicals, MCOPPB should be handled with care. Appropriate safety measures, including the use of personal protective equipment (PPE) and adherence to laboratory safety protocols, are essential when working with this compound.
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Contributors: Prab R. Tumpati, MD