Zenazocine
Zenazocine is a drug that belongs to the benzomorphan class of opioids. It was developed in the 1970s by the pharmaceutical company Sterling Drug. Zenazocine is an opioid analgesic drug, which means it is used to relieve pain. It is also a kappa opioid receptor agonist, which means it binds to and activates kappa opioid receptors in the brain and spinal cord to produce its pain-relieving effects.
History[edit]
Zenazocine was first synthesized in the 1970s by the pharmaceutical company Sterling Drug. It was developed as part of a series of opioid analgesics, which also included pentazocine and phenazocine. However, unlike these other drugs, zenazocine was never marketed for medical use.
Pharmacology[edit]
Zenazocine is a kappa opioid receptor agonist. This means it binds to and activates kappa opioid receptors in the brain and spinal cord. Activation of these receptors produces analgesia, or pain relief. However, kappa opioid receptor agonists can also produce side effects such as dysphoria (a state of unease or dissatisfaction), hallucinations, and diuresis (increased urine production).
Side Effects[edit]
The side effects of zenazocine are similar to those of other kappa opioid receptor agonists. These can include dysphoria, hallucinations, and diuresis. Other potential side effects include nausea, vomiting, and constipation. As with all opioids, there is also the risk of addiction and overdose.
See Also[edit]
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Zenazocine[edit]
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Chemical structure of Zenazocine -
3D ball model of Zenazocine
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