Anileridine
Anileridine (pronounced: an-il-er-i-deen) is a synthetic opioid analgesic drug and a derivative of pethidine (meperidine). It was developed in the 1950s during research into analogues of pethidine and was assessed by the United Nations Office on Drugs and Crime (UNODC) in 1955 but was not marketed in the United States until 1959.
Etymology
The term "Anileridine" is derived from the chemical structure of the drug, which is an anilide of pethidine, hence the name "Anileridine".
Pharmacology
Anileridine works by binding to the mu-opioid receptors in the brain and spinal cord. This binding blocks the transmission of pain signals sent by the nerves to the brain, thereby reducing the sensation of pain.
Related Terms
- Opioid: A class of drugs that include the illegal drug heroin, synthetic opioids such as fentanyl, and pain relievers available legally by prescription, such as oxycodone (OxyContin®), hydrocodone (Vicodin®), codeine, morphine, and many others.
- Pethidine: A synthetic opioid pain medication of the phenylpiperidine class.
- Mu-opioid receptors: A class of opioid receptors with high affinity for enkephalins and beta-endorphin, but low affinity for dynorphins.
Side Effects
Like other opioids, anileridine can cause a variety of side effects, including drowsiness, dizziness, nausea, vomiting, constipation, and respiratory depression. It also carries a risk of dependency and withdrawal symptoms if used for extended periods.
Legal Status
In the United States, anileridine is a Schedule II controlled substance, which means it has a high potential for abuse and is available legally only by prescription.
External links
- Medical encyclopedia article on Anileridine
- Wikipedia's article - Anileridine
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