Asimadoline
Asimadoline (pronounced as-ee-mad-oh-leen) is a drug that is primarily used in the treatment of Irritable Bowel Syndrome (IBS). It is a kappa opioid receptor agonist, meaning it binds to and activates these receptors in the body.
Etymology
The term "Asimadoline" is derived from the Greek words "Asi" meaning "without" and "madoline" meaning "pain". This is in reference to the drug's primary function as a pain reliever.
Pharmacology
Asimadoline works by binding to the kappa opioid receptors in the gut. This reduces the sensation of pain and discomfort, making it effective in the treatment of IBS. It is a peripherally selective drug, meaning it primarily affects the peripheral nervous system rather than the central nervous system. This reduces the risk of central side effects such as sedation or euphoria.
Clinical Use
Asimadoline is used in the treatment of IBS, particularly in cases where pain and discomfort are the primary symptoms. It has been shown to be effective in reducing these symptoms and improving quality of life for patients with this condition.
Related Terms
See Also
External links
- Medical encyclopedia article on Asimadoline
- Wikipedia's article - Asimadoline
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