Sufentanil

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Sufentanil

Sufentanil (/suːˈfɛntənɪl/), also known as N-[4-(methoxymethyl)-1-[2-(2-thienyl)ethyl]-4-piperidinyl]-N-phenylpropanamide, is a potent synthetic opioid analgesic drug. It is used in medicine for its analgesic properties and is often administered in clinical settings for pain management.

Etymology

The term "Sufentanil" is derived from the chemical structure of the drug, which is a modification of the structure of Fentanyl, a powerful synthetic opioid. The prefix "Su-" is derived from the Latin "super-" meaning "above" or "beyond", indicating the drug's increased potency compared to Fentanyl.

Pharmacology

Sufentanil is approximately 5 to 10 times more potent than its parent drug, Fentanyl. It works by binding to the mu-opioid receptor in the brain, which are receptors involved in pain perception. This binding action results in a decrease in the perception of pain.

Medical Uses

Sufentanil is used in the medical field for the management of severe pain. It is often used in surgical procedures, in the intensive care unit, and for chronic pain management. It is also used in combination with other medications for anesthesia.

Side Effects

Like other opioids, Sufentanil can cause a range of side effects. These can include nausea, vomiting, constipation, and respiratory depression. It can also cause psychological effects such as euphoria and dependence.

Related Terms

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