List of Schedule V controlled substances (U.S.)

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(Redirected from List of Schedule V drugs (US))

List of Schedule V controlled substances in the United States


Overview

Lyrica, a brand name for pregabalin, is not a Schedule V substance but is often discussed in the context of controlled substances.

In the United States, controlled substances are categorized into five schedules under the Controlled Substances Act (CSA). These schedules are determined based on the substance's potential for abuse, accepted medical use, and safety or dependence liability. Schedule V substances are considered to have a lower potential for abuse relative to substances listed in Schedule IV.

Characteristics of Schedule V Substances

Schedule V controlled substances are defined by the following characteristics:

  • They have a low potential for abuse relative to substances in Schedule IV.
  • They have a currently accepted medical use in treatment in the United States.
  • Abuse of the drug or other substance may lead to limited physical dependence or psychological dependence relative to the substances in Schedule IV.

Common Schedule V Substances

Schedule V substances often include medications that contain limited quantities of certain narcotics. These substances are typically used for antitussive, antidiarrheal, and analgesic purposes. Some common examples include:

  • Codeine preparations: These are often used in cough preparations. For example, cough syrups containing not more than 200 milligrams of codeine per 100 milliliters or per 100 grams.
  • Diphenoxylate preparations: When combined with atropine, diphenoxylate is used to treat diarrhea. The combination is known as Lomotil.
  • Pregabalin: Although not a Schedule V substance in the U.S., pregabalin is often discussed in the context of controlled substances due to its regulation in other countries.

Legal Implications

The classification of a substance as Schedule V has specific legal implications. Prescriptions for Schedule V substances can be refilled more times than those for higher schedules, and in some states, they may be available over the counter. However, they are still subject to regulation and monitoring to prevent misuse and abuse.

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Contributors: Prab R. Tumpati, MD