Intrahepatic cholestasis of pregnancy

Intrahepatic cholestasis of pregnancy (pronunciation: in-truh-hep-uh-tik koh-luh-stey-sis of preg-nuhn-see) is a liver disorder that occurs in pregnant women. It affects the normal flow of bile, a digestive fluid produced by the liver. The condition can cause severe itching and may increase the risk of preterm birth and stillbirth.

Etymology

The term "Intrahepatic cholestasis of pregnancy" is derived from the following medical terms: "Intrahepatic" (within the liver), "cholestasis" (a condition where bile cannot flow from the liver to the duodenum), and "pregnancy".

Symptoms

The main symptom of intrahepatic cholestasis of pregnancy is severe itching (pruritus), especially on the palms of the hands and soles of the feet. Other symptoms may include yellowing of the skin and whites of the eyes (jaundice), dark urine, and pale stools.

Causes

Intrahepatic cholestasis of pregnancy is thought to be caused by a combination of hormonal, genetic, and environmental factors. It is more common in women with a family history of the condition and in certain ethnic groups.

Diagnosis

Diagnosis of intrahepatic cholestasis of pregnancy is based on symptoms, blood tests to measure bile acid levels, and liver function tests. In some cases, an ultrasound may be used to rule out other causes of liver disease.

Treatment

Treatment for intrahepatic cholestasis of pregnancy aims to relieve symptoms and reduce the risk of complications. This may include medication to reduce bile acids, vitamin K supplements to prevent bleeding, and regular monitoring of the baby's health.

Related Terms

• Liver
• Bile
• Jaundice
• Ultrasound
• Pregnancy

External links

• Medical encyclopedia article on Intrahepatic cholestasis of pregnancy
• Wikipedia's article - Intrahepatic cholestasis of pregnancy

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