Pruritic urticarial papules and plaques of pregnancy

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A skin condition that occurs during pregnancy


Pruritic urticarial papules and plaques of pregnancy
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Synonyms PUPPP, polymorphic eruption of pregnancy
Pronounce N/A
Field Dermatology
Symptoms Itchy, red, raised bumps and patches on the skin
Complications N/A
Onset Third trimester of pregnancy
Duration Until delivery or shortly after
Types N/A
Causes Unknown
Risks First pregnancy, multiple pregnancies
Diagnosis Clinical examination, skin biopsy
Differential diagnosis Pemphigoid gestationis, Intrahepatic cholestasis of pregnancy, Atopic eruption of pregnancy
Prevention N/A
Treatment Topical corticosteroids, antihistamines
Medication N/A
Prognosis Excellent, resolves after delivery
Frequency 1 in 160 pregnancies
Deaths N/A


Pruritic urticarial papules and plaques of pregnancy (PUPPP), also known as polymorphic eruption of pregnancy, is a skin condition that occurs during the third trimester of pregnancy. It is characterized by itchy, red, raised bumps and patches on the skin, primarily affecting the abdomen, but can also spread to the thighs, buttocks, and arms.

Symptoms[edit]

The primary symptom of PUPPP is intense pruritus (itching) accompanied by the appearance of red, raised bumps and patches. These lesions often start in the striae distensae (stretch marks) and can spread to other parts of the body. The condition typically spares the face, palms, and soles.

Causes[edit]

The exact cause of PUPPP is unknown. It is more common in first pregnancies and multiple pregnancies, suggesting a possible link to hormonal changes or skin stretching.

Diagnosis[edit]

Diagnosis is primarily based on clinical examination. A skin biopsy may be performed to rule out other conditions such as pemphigoid gestationis, intrahepatic cholestasis of pregnancy, and atopic eruption of pregnancy.

Treatment[edit]

Treatment focuses on relieving symptoms. Topical corticosteroids and antihistamines are commonly prescribed. In severe cases, oral corticosteroids may be considered. The condition usually resolves on its own shortly after delivery.

Prognosis[edit]

The prognosis for PUPPP is excellent. Symptoms typically resolve within a few days to weeks after delivery, and there are no long-term effects on the mother or baby.

Related Pages[edit]



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