Serotonin reuptake inhibitor

Serotonin reuptake inhibitor

A Serotonin reuptake inhibitor (SRI) is a type of drug that acts as a reuptake inhibitor of the neurotransmitter serotonin (5-hydroxytryptamine (5-HT)) by blocking the action of the serotonin transporter (SERT). This leads to increased extracellular concentrations of serotonin and, therefore, an increase in serotonergic neurotransmission. It is a commonly used type of drug in the treatment of various forms of depression, anxiety disorders, and some personality disorders.

Pronunciation

Serotonin reuptake inhibitor: /sɛrəˈtoʊnɪn riˈʌptɛk ɪnˈhɪbɪtər/

Etymology

The term "Serotonin reuptake inhibitor" is derived from its function. "Serotonin" is a neurotransmitter that helps transmit signals in the brain. "Reuptake inhibitor" refers to the mechanism of the drug, which inhibits the reuptake of serotonin, thereby increasing the amount of serotonin available in the brain.

Related Terms

• Selective serotonin reuptake inhibitors (SSRIs)
• Serotonin-norepinephrine reuptake inhibitors (SNRIs)
• Norepinephrine-dopamine reuptake inhibitors (NDRIs)
• Tricyclic antidepressants (TCAs)
• Monoamine oxidase inhibitors (MAOIs)

See Also

• Neurotransmitter
• Serotonin
• Depression
• Anxiety disorders
• Personality disorders

External links

• Medical encyclopedia article on Serotonin reuptake inhibitor
• Wikipedia's article - Serotonin reuptake inhibitor

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