BD1063

BD1063.png

BD1063 is a selective sigma-1 receptor antagonist. It is primarily used in scientific research to study the role of sigma-1 receptors in various physiological and pathological processes.

Chemical Properties

BD1063 is a chemical compound with the IUPAC name N-[2-(3,4-dichlorophenyl)ethyl]-N-methyl-2-(1-pyrrolidinyl)ethanamine. It has a molecular formula of C₁₅H₂₂Cl₂N₂ and a molecular weight of 301.26 g/mol.

Pharmacology

BD1063 acts as a selective antagonist at the sigma-1 receptor, a type of sigma receptor that is involved in the modulation of ion channels, neurotransmitter release, and cell signaling pathways. By blocking the sigma-1 receptor, BD1063 helps researchers understand the receptor's role in various conditions, including neurological disorders, pain, and drug addiction.

Research Applications

BD1063 is widely used in preclinical studies to investigate the therapeutic potential of sigma-1 receptor antagonists. It has been studied in models of neuropathic pain, depression, and schizophrenia. Additionally, BD1063 has been used to explore the sigma-1 receptor's involvement in cancer and neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease.

Safety and Toxicity

As with many research chemicals, the safety and toxicity profile of BD1063 is not fully established. It is primarily used in controlled laboratory settings, and its effects in humans are not well-documented.

See Also

• Sigma receptor
• Sigma-1 receptor
• Neuropathic pain
• Depression
• Schizophrenia
• Alzheimer's disease
• Parkinson's disease

External Links

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