Piperidylthiambutene
Piperidylthiambutene is a synthetic opioid analgesic drug, which is part of the larger family of opioids that includes natural, semi-synthetic, and synthetic substances. It is a derivative of the opioid alkaloid thebaine that is found in the opium poppy (Papaver somniferum).
Chemistry
Piperidylthiambutene is chemically classified as a thiambutene, which is a subclass of opioids. It is structurally related to other thiambutenes such as moramide intermediate and dimethylthiambutene. The chemical structure of piperidylthiambutene consists of a thiambutene core, which is a four-membered ring with a sulfur atom, and a piperidine ring attached to it.
Pharmacology
As an opioid, piperidylthiambutene primarily acts on the mu-opioid receptor, which is responsible for the drug's analgesic effects. It may also have activity at the kappa-opioid receptor and delta-opioid receptor, but this is less well understood. Like other opioids, piperidylthiambutene can cause physical dependence and addiction, and its use is associated with a risk of overdose.
Legal Status
The legal status of piperidylthiambutene varies by country. In some countries, it is a controlled substance, meaning its manufacture, distribution, and use are regulated by law. In others, it may be legal for medical use but illegal for recreational use.
See Also
- Opioid
- Thebaine
- Papaver somniferum
- Thiambutene
- Moramide intermediate
- Dimethylthiambutene
- Mu-opioid receptor
- Kappa-opioid receptor
- Delta-opioid receptor
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Contributors: Prab R. Tumpati, MD