Familial adenomatous polyposis
| Familial adenomatous polyposis | |
|---|---|
| Term | Familial adenomatous polyposis |
| Short definition | familial adenomatous polyposis (fuh-MIH-lee-ul A-deh-NOH-muh-tus PAH-lee-POH-sis) An inherited disease in which many polyps (usually hundreds to thousands) form on the inner walls of the colon and rectum. Polyps are abnormal growths that can become cancer if not removed. |
| Type | Cancer terms |
| Specialty | Oncology |
| Language | English |
| Source | NCI |
| Comments | |
familial adenomatous polyposis - (pronounced) (fuh-MIH-lee-ul A-deh-NOH-muh-tus PAH-lee-POH-sis) An inherited disease in which many polyps (usually hundreds to thousands) form on the inner walls of the colon and rectum. Polyps are abnormal growths that can become cancer if not removed. People with familial adenomatous polyposis have a very high risk of developing colon cancer early on, and also have an increased risk of developing cancers of the stomach, small intestine, pancreas, bile duct, liver, adrenal gland, thyroid, and brain. They can also have dental and eye problems, and benign (noncancerous) tumors in the stomach, small intestine, bones, soft tissues, skin, and adrenal glands. Familial adenomatous polyposis is caused by mutations (changes) in a gene called APC, which are inherited in an autosomal dominant manner. It's a kind of hereditary cancer syndrome. Also called classic familial adenomatous polyposis, classic familial polyposis, classic FAP and FAP
External links
- Medical encyclopedia article on Familial adenomatous polyposis
- Wikipedia's article - Familial adenomatous polyposis
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