Pancreatoblastoma
Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC
Pancreatoblastoma | |
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Synonyms | Infantile pancreatic carcinoma |
Pronounce | N/A |
Specialty | N/A |
Symptoms | Abdominal pain, weight loss, jaundice |
Complications | Metastasis, diabetes mellitus |
Onset | Typically in childhood |
Duration | Variable |
Types | |
Causes | Unknown |
Risks | Genetic predisposition, Beckwith-Wiedemann syndrome, familial adenomatous polyposis |
Diagnosis | Imaging studies, biopsy |
Differential diagnosis | Pancreatic adenocarcinoma, neuroblastoma, hepatoblastoma |
Prevention | |
Treatment | Surgery, chemotherapy |
Medication | |
Prognosis | Variable, depends on stage at diagnosis |
Frequency | Very rare |
Deaths | N/A |
Pancreatoblastoma is a rare type of cancer that primarily affects children. It is a malignant tumor that originates in the pancreas, specifically in the cells responsible for producing digestive enzymes.
Symptoms
The symptoms of pancreatoblastoma can vary, but often include abdominal pain, nausea, vomiting, and jaundice. In some cases, the tumor may be discovered during a routine physical examination or imaging study.
Causes
The exact cause of pancreatoblastoma is unknown. However, it is believed to be associated with certain genetic conditions, such as Beckwith-Wiedemann syndrome and familial adenomatous polyposis.
Diagnosis
Diagnosis of pancreatoblastoma typically involves a combination of physical examination, imaging studies, and biopsy. Imaging studies such as ultrasound, computed tomography (CT) scan, and magnetic resonance imaging (MRI) can help to identify the location and size of the tumor. A biopsy, in which a small sample of tissue is removed for examination under a microscope, can confirm the diagnosis.
Treatment
Treatment for pancreatoblastoma usually involves surgery to remove the tumor, followed by chemotherapy to kill any remaining cancer cells. In some cases, radiation therapy may also be used. The prognosis for children with pancreatoblastoma is generally good, with a survival rate of over 80% with appropriate treatment.
See also
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Contributors: Prab R. Tumpati, MD