Pancreatoblastoma

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Pancreatoblastoma
Relative incidence of pancreatic neoplasms.png
Synonyms Infantile pancreatic carcinoma
Pronounce N/A
Specialty N/A
Symptoms Abdominal pain, weight loss, jaundice
Complications Metastasis, diabetes mellitus
Onset Typically in childhood
Duration Variable
Types
Causes Unknown
Risks Genetic predisposition, Beckwith-Wiedemann syndrome, familial adenomatous polyposis
Diagnosis Imaging studies, biopsy
Differential diagnosis Pancreatic adenocarcinoma, neuroblastoma, hepatoblastoma
Prevention
Treatment Surgery, chemotherapy
Medication
Prognosis Variable, depends on stage at diagnosis
Frequency Very rare
Deaths N/A


Pancreatoblastoma is a rare type of cancer that primarily affects children. It is a malignant tumor that originates in the pancreas, specifically in the cells responsible for producing digestive enzymes.

Symptoms

The symptoms of pancreatoblastoma can vary, but often include abdominal pain, nausea, vomiting, and jaundice. In some cases, the tumor may be discovered during a routine physical examination or imaging study.

Causes

The exact cause of pancreatoblastoma is unknown. However, it is believed to be associated with certain genetic conditions, such as Beckwith-Wiedemann syndrome and familial adenomatous polyposis.

Diagnosis

Diagnosis of pancreatoblastoma typically involves a combination of physical examination, imaging studies, and biopsy. Imaging studies such as ultrasound, computed tomography (CT) scan, and magnetic resonance imaging (MRI) can help to identify the location and size of the tumor. A biopsy, in which a small sample of tissue is removed for examination under a microscope, can confirm the diagnosis.

Treatment

Treatment for pancreatoblastoma usually involves surgery to remove the tumor, followed by chemotherapy to kill any remaining cancer cells. In some cases, radiation therapy may also be used. The prognosis for children with pancreatoblastoma is generally good, with a survival rate of over 80% with appropriate treatment.

See also

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Contributors: Prab R. Tumpati, MD