Colorectal adenoma

Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC

Colorectal adenoma
Tubulovillous adenoma
Synonyms	Adenomatous polyp
Pronounce	N/A
Specialty	N/A
Symptoms	Often asymptomatic, may cause rectal bleeding
Complications	Colorectal cancer
Onset	Typically in adults over 50
Duration	Can persist until removed
Types	Tubular adenoma, Villous adenoma, Tubulovillous adenoma
Causes	Genetic mutations, dietary factors
Risks	Age, family history, diet high in red meat
Diagnosis	Colonoscopy, biopsy
Differential diagnosis	Hyperplastic polyp, inflammatory polyp
Prevention	Regular screening, dietary changes
Treatment	Polypectomy, surgical resection
Medication	N/A
Prognosis	Good if removed early
Frequency	Common in adults over 50
Deaths	N/A

Colorectal adenoma is a type of polyp that is found in the colon or rectum. Colorectal adenomas are considered precancerous conditions, as they can develop into colorectal cancer if left untreated.

Types of Colorectal Adenoma

There are three main types of colorectal adenomas: tubular adenomas, villous adenomas, and tubulovillous adenomas.

• Tubular adenoma is the most common type of colorectal adenoma. It is typically small and has a lower risk of becoming cancerous compared to other types of adenomas.
• Villous adenoma is less common but more likely to become cancerous. It is often larger and has a villous or "finger-like" appearance under the microscope.
• Tubulovillous adenoma is a mix of tubular and villous adenoma. It has an intermediate risk of becoming cancerous.

Risk Factors

Several factors can increase the risk of developing colorectal adenomas. These include age, a history of colorectal adenomas or colorectal cancer, certain genetic syndromes such as Lynch syndrome and Familial adenomatous polyposis, and lifestyle factors such as diet, smoking, and lack of physical activity.

Diagnosis

Colorectal adenomas are often found during a colonoscopy or sigmoidoscopy. If an adenoma is found, it is usually removed and sent to a lab for testing. The lab can confirm whether the polyp is an adenoma and whether it has any signs of cancer.

Treatment

The primary treatment for colorectal adenomas is removal during a colonoscopy or sigmoidoscopy. This is usually done using a procedure called a polypectomy. In some cases, if the adenoma is very large or if there are many adenomas, surgery may be needed.

Prevention

Prevention strategies for colorectal adenomas include regular screening with colonoscopy or sigmoidoscopy, maintaining a healthy diet, regular physical activity, and avoiding smoking.

Gallery

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  Tubulovillous adenoma

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  Pie chart of colorectal polyp etiologies

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  Non-proliferative versus proliferative colonic crypts

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  Histopathology of high-grade dysplasia in tubulovillous adenoma, annotated

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  Villous adenoma

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  Sessile serrated adenoma, very high magnification

See Also

• Colorectal cancer
• Colonoscopy
• Polyp
• Lynch syndrome
• Familial adenomatous polyposis

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