Dynein

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Dynein

Dynein (/ˈdaɪniːn/) is a family of cytoskeletal motor proteins that move along microtubules in cells. They convert the chemical energy stored in ATP to mechanical work.

Etymology

The term "dynein" (dyne + -in) derives from the Greek word "dyne" meaning force, and the suffix "-in" used for proteins.

Function

Dyneins transport various cellular cargos, provide forces and displacements important in mitosis, and probably have many other roles yet to be understood. Dyneins can be divided into two groups: cytoplasmic dynein, which moves along microtubules in the cytoplasm, and axonemal dynein, which is a component of cilia and flagella.

Structure

Dynein is a complex protein composed of many smaller subunits. The structure of dynein includes a heavy chain containing the motor domains capable of force generation, and several smaller light and intermediate chains.

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