Panomifene

Panomifene
INN
Drug class
Routes of administration
Pregnancy category
Bioavailability
Metabolism
Elimination half-life
Excretion
Legal status
CAS Number	77599-17-8
PubChem	3033654
DrugBank
ChemSpider	2298282
KEGG

Panomifene (INN) (former developmental code names GYKI-13504, EGIS-5650) is a nonsteroidal selective estrogen receptor modulator (SERM) of the triphenylethylene group related to tamoxifen that was under development as an antineoplastic agent by Egis Pharmaceuticals and IVAX Drug Research Institute in the 1990s for the treatment of breast cancer but was not marketed.<ref name="Elks2014">{{{last}}},

 J. Elks, 
  
 The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. online version, 
  
 Springer, 
  
  
  
 ISBN 978-1-4757-2085-3, 
  
  
  
 Pages: 930–,</ref><ref name="AdisInsight">http://adisinsight.springer.com/drugs/800002425</ref><ref name="OettelSchillinger2012a">, 
  
 Estrogens and Antiestrogens I: Physiology and Mechanisms of Action of Estrogens and Antiestrogens. online version, 
  
 Springer Science & Business Media, 
  
  
  
 ISBN 978-3-642-58616-3, 
  
  
  
 Pages: 60–,</ref><ref name="OettelSchillinger2012b">, 
  
 Estrogens and Antiestrogens II: Pharmacology and Clinical Application of Estrogens and Antiestrogen. online version, 
  
 Springer Science & Business Media, 
  
  
  
 ISBN 978-3-642-60107-1, 
  
  
  
 Pages: 292–,</ref><ref name="DixneufBruneau2014">, 
  
 Ruthenium in Catalysis. online version, 
  
 Springer, 
  
  
  
 ISBN 978-3-319-08482-4, 
  
  
  
 Pages: 385–,</ref><ref name="pmid9328614">, 
 Antiestrogens, antiandrogens, 
 Acta Physiol Hung, 
 1996,
 Vol. 84(Issue: 4),
 pp. 405–6,
 
 PMID: 9328614,</ref> It reached phase II clinical trials before development was terminated.<ref name="AdisInsight" /> The drug was described in 1981.<ref name="Elks2014" />

External links

• Panomifene - AdisInsight

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