Triphenylethylene

Triphenylethylene (pronunciation: tri-fen-yl-eth-yl-een) is a chemical compound that is often used as a base structure in the synthesis of various pharmaceutical drugs.

Etymology

The term "triphenylethylene" is derived from its chemical structure, which consists of three phenyl groups attached to an ethylene group. The prefix "tri-" is from the Greek "τρι-" meaning "three", "phenyl" is derived from the Greek "φαίνω" (phaino) meaning "to show", and "ethylene" is derived from the Greek "αιθήρ" (aither) meaning "ether".

Related Terms

Phenyl group: A functional group in organic chemistry that consists of six carbon atoms bonded in a hexagonal planar ring to one hydrogen atom.
Ethylene group: A type of hydrocarbon group that consists of two carbon atoms double-bonded to each other.
Estrogen receptor: A group of proteins found inside cells that are activated by the hormone estrogen. Triphenylethylene derivatives such as Tamoxifen and Clomifene are known to interact with these receptors.
Selective estrogen receptor modulator: A type of drug that acts on the estrogen receptor. Triphenylethylene is used as a base structure in the synthesis of some of these drugs.

Uses

Triphenylethylene is not typically used on its own, but its derivatives have a wide range of applications in the medical field. For example, the triphenylethylene derivative Tamoxifen is commonly used in the treatment of Breast cancer, while Clomifene is used in the treatment of infertility in women.

External links

Medical encyclopedia article on Triphenylethylene
Wikipedia's article - Triphenylethylene

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Triphenylethylene