Ro67-4853

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Ro67-4853

Ro67-4853 (/roʊˈsɪkstiːˈfɔːrˈfaɪvˈθriː/) is a pharmacological compound of interest in the field of neuroscience.

Etymology

The name "Ro67-4853" is derived from the naming convention used by the pharmaceutical company Roche, which discovered the compound. The "Ro" stands for Roche, while the numbers "67-4853" are a unique identifier for the compound.

Description

Ro67-4853 is a potent and selective antagonist of the NMDA receptor, specifically targeting the NR2B subunit. The NMDA receptor is a type of ionotropic glutamate receptor that is important for controlling synaptic plasticity and memory function. By blocking this receptor, Ro67-4853 can modulate these processes.

Related Terms

  • NMDA receptor antagonist: A type of drug that reduces the activity of the NMDA receptors in the brain. Ro67-4853 is a specific type of NMDA receptor antagonist.
  • Neuropharmacology: The study of how drugs affect cellular function in the nervous system. Ro67-4853 is a compound of interest in this field.
  • Synaptic plasticity: The ability of synapses to strengthen or weaken over time, in response to increases or decreases in their activity. Ro67-4853 can modulate this process by blocking NMDA receptors.
  • Memory function: The cognitive process that allows information to be encoded, stored, and retrieved. Ro67-4853 can affect this process by modulating the activity of NMDA receptors.

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