Propoxyphene

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Propoxyphene

Propoxyphene (/prəˈpɒksɪfiːn/) is a narcotic analgesic drug that was widely used for the relief of mild to moderate pain before its withdrawal from the market in many countries due to safety concerns.

Etymology

The term "Propoxyphene" is derived from its chemical name, propoxyphene hydrochloride. The prefix "prop-" refers to its three carbon chain, "oxy-" refers to the oxygen atom in its structure, and "-phene" is derived from the Greek word "phainein", meaning "to show", referring to its visibility under a microscope.

Usage

Propoxyphene was primarily used to treat mild to moderate pain. It was also used in combination with acetaminophen (paracetamol) or aspirin for more effective pain relief and as a cough suppressant, due to its effects on the central nervous system.

Side Effects

Common side effects of propoxyphene include dizziness, sedation, nausea, and vomiting. More serious side effects can include respiratory depression, cardiac arrhythmias, and dependence.

Withdrawal

Propoxyphene was withdrawn from the market in the United States in 2010 by the Food and Drug Administration (FDA) due to concerns about its potential to cause heart rhythm abnormalities. Similar actions were taken in the European Union and Canada.

Related Terms

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