CCL28
CCL28, also known as mucosae-associated epithelial chemokine (MEC) or C-C motif chemokine 28, is a protein that in humans is encoded by the CCL28 gene. It is a member of the CC chemokine family, and its primary function is to attract immune cells to sites of inflammation.
Function
CCL28 is a chemokine that is produced by a variety of cells, including epithelial cells and leukocytes. It is involved in the immune response by attracting immune cells to sites of inflammation. CCL28 is also involved in the homing of T cells and IgA antibody-secreting cells to the mucosal tissues.
Clinical significance
CCL28 has been implicated in a number of diseases, including asthma, allergic rhinitis, and inflammatory bowel disease. It has also been associated with tumor growth and metastasis in certain types of cancer.
See also
References
External links
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Contributors: Prab R. Tumpati, MD
