IFNA14

IFNA14 is a protein that in humans is encoded by the IFNA14 gene. The protein encoded by this gene is a member of the interferon family. Interferons are proteins released by host cells in response to the presence of pathogens such as viruses, bacteria, parasites or tumor cells. They allow communication between cells to trigger the protective defenses of the immune system that eradicate pathogens or tumors.

Function

Interferons are produced by a wide variety of cells in response to the presence of double-stranded RNA, a key indicator of viral infection. Interferons are named for their ability to "interfere" with viral replication by protecting cells from virus infections. IFNA14, like other interferons, is thought to have antiviral, antiproliferative, and immunomodulatory effects.

Gene

The IFNA14 gene is located on the short (p) arm of chromosome 9 at position 22, from base pair 21,196,053 to base pair 21,197,053.

Clinical significance

Interferons, including IFNA14, have therapeutic applications in the treatment of a variety of diseases, including viral infections like hepatitis B and hepatitis C, cancers like leukemia, lymphoma, and certain autoimmune diseases.

See also

• Interferon
• Interferon type I
• Chromosome 9

External links

• IFNA14 at the National Center for Biotechnology Information