Bone development

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Bone Development

Bone development, also known as Osteogenesis, is the process by which bones form in the body. Pronounced as os·te·o·gen·e·sis, the term originates from the Greek words "osteon," meaning bone, and "genesis," meaning creation.

Process

Bone development begins in the embryonic stage and continues throughout adulthood. It involves two primary methods: Intramembranous ossification and Endochondral ossification.

Intramembranous ossification (pronounced as in·tra·mem·bra·nous os·si·fi·ca·tion) is the process by which flat bones like the skull and clavicle are formed directly from mesenchymal tissue.

Endochondral ossification (pronounced as en·do·chon·dral os·si·fi·ca·tion) is the process by which all other bones are formed. This process involves the replacement of hyaline cartilage with bony tissue.

Stages of Bone Development

The stages of bone development include:

  1. Ossification center formation: This is the initial stage of bone development where the future bone begins to form.
  2. Calcification: In this stage, calcium and other minerals are deposited into the bone matrix, hardening the bone.
  3. Formation of the Trabeculae: The trabeculae are the spongy part of the bone that provides support and structure.
  4. Development of the Periosteum: The periosteum is a membrane that covers the outer surface of all bones, except at the joints of long bones.

Related Terms

  • Osteoblast: A cell that secretes the matrix for bone formation.
  • Osteoclast: A large multinucleate cell associated with the absorption and removal of bone.
  • Osteocyte: A bone cell, formed when an osteoblast becomes embedded in the matrix it has secreted.
  • Chondrocyte: A cell which has secreted the matrix of cartilage and become embedded in it.

External links

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