Endochondral ossification
Endochondral Ossification
Endochondral ossification (pronunciation: en-doh-KON-druhl os-see-fi-KAY-shun) is a specific process in the development of the mammalian skeletal system. This process involves the formation of bone tissue from cartilage.
Etymology
The term "endochondral ossification" is derived from the Greek words "endo" meaning within, "chondros" meaning cartilage, and "ossification" from the Latin "os" meaning bone and "ficare" meaning to make. Thus, it refers to the process of making bone within cartilage.
Process
Endochondral ossification begins with points in the cartilage called "primary ossification centers." These centers are responsible for the initial formation of bone. The process continues with the development of "secondary ossification centers," which contribute to the growth and elongation of the bone.
Related Terms
- Ossification: The process of bone formation.
- Intramembranous ossification: Another method of bone formation, where bone develops from mesenchymal tissue.
- Chondrocyte: A cell that has secreted the matrix of cartilage and become embedded in it.
- Osteoblast: A cell that secretes the matrix for bone formation.
- Osteoclast: A large multinucleate cell associated with the absorption and removal of bone.
See Also
External links
- Medical encyclopedia article on Endochondral ossification
- Wikipedia's article - Endochondral ossification
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