Lamellae

From WikiMD's medical encyclopedia

Lamellae are thin layers, plates, or scales of material. They are a common microstructure seen in many different materials and can have very different properties depending on the context. In the medical field, lamellae are often seen in bone and cartilage, where they help to provide strength and flexibility.

Anatomy

In the context of anatomy, lamellae are thin layers of bone or cartilage that are arranged in a concentric pattern around a central canal, known as a Haversian canal. This structure is known as a Haversian system or osteon, and is the fundamental functional unit of compact bone.

Lamellae can be classified into three types: concentric lamellae, interstitial lamellae, and circumferential lamellae.

  • Concentric lamellae are circular layers of bone matrix that surround the central canal within an osteon.
  • Interstitial lamellae are the remnants of concentric lamellae that were partially removed during bone remodeling.
  • Circumferential lamellae are layers of bone matrix that run along the outer circumference of the bone, providing resistance to torsional forces.

Physiology

The lamellae in bone serve several important functions. They help to provide the bone with its strength and rigidity, while also allowing for some degree of flexibility. The arrangement of the lamellae in concentric circles around a central canal allows for the efficient distribution of nutrients and the removal of waste products.

In addition to their structural role, the lamellae also play a role in the body's calcium homeostasis. The bone tissue in the lamellae contains large amounts of calcium, which can be released into the bloodstream when needed.

Pathology

Abnormalities in the structure or function of the lamellae can lead to a variety of medical conditions. For example, osteoporosis is a condition characterized by a decrease in bone mass and density, which can lead to an increased risk of fractures. This is often due to a decrease in the number or thickness of the lamellae.

Osteogenesis imperfecta, also known as brittle bone disease, is another condition that can be caused by defects in the lamellae. This is a genetic disorder that affects the body's ability to produce collagen, a protein that is an important component of the lamellae.

See also

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