3-Methylamphetamine: Difference between revisions

Latest revision as of 04:21, 9 January 2025

3-Methylamphetamine

3-Methylamphetamine is a chemical compound that belongs to the class of substituted amphetamines. It is a structural analog of amphetamine, with a methyl group attached to the third carbon of the phenethylamine backbone.

Chemical Structure[edit]

3-Methylamphetamine is characterized by the presence of a methyl group at the third position of the amphetamine structure. This modification alters its pharmacological properties compared to other amphetamines such as amphetamine and methamphetamine.

Pharmacology[edit]

The pharmacological effects of 3-Methylamphetamine are similar to those of other amphetamines, which typically act as central nervous system stimulants. These effects are primarily due to the compound's ability to increase the release of neurotransmitters such as dopamine, norepinephrine, and serotonin in the brain.

Mechanism of Action[edit]

3-Methylamphetamine acts by promoting the release of monoamines from presynaptic neurons. It is believed to enter the neuron via the dopamine transporter and then induce the release of dopamine into the synaptic cleft. This action is similar to that of other substituted amphetamines.

Legal Status[edit]

The legal status of 3-Methylamphetamine varies by country. In many jurisdictions, it is classified as a controlled substance due to its potential for abuse and lack of accepted medical use. It is important to consult local regulations to determine its legal status in a specific area.

Synthesis[edit]

The synthesis of 3-Methylamphetamine involves the alkylation of amphetamine precursors. This process typically requires specialized knowledge in organic chemistry and access to controlled substances, making it illegal in many regions without proper authorization.

Potential Uses[edit]

While 3-Methylamphetamine has no accepted medical uses, it is sometimes studied in research settings to understand the effects of structural modifications on the activity of amphetamine-like compounds. These studies can provide insights into the development of new therapeutic agents.

Related Compounds[edit]

3-Methylamphetamine is related to several other compounds in the amphetamine family, including:

Amphetamine
Methamphetamine
3,4-Methylenedioxyamphetamine (MDA)
3,4-Methylenedioxymethamphetamine (MDMA)

Related Pages[edit]

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--Methylamphetamine (3-MeA; PAL-314) is a stimulant drug from the amphetamine family. It is self-administered by mice to a similar extent to 4-fluoroamphetamine and has comparable properties as a monoamine releaser, although with a more balanced release of all three monoamines, as opposed to the more dopamine/noradrenaline selective fluoro analogues.
+[[File:3-Methylamphetamine.svg|thumb]]<br>3-Methylamphetamine
-{{stb}}
-{{dictionary-stub1}}
+-Methylamphetamine is a chemical compound that belongs to the class of substituted amphetamines. It is a structural analog of amphetamine, with a methyl group attached to the third carbon of the phenethylamine backbone.
-{{short-articles-ni}}
+==Chemical Structure==
+-Methylamphetamine is characterized by the presence of a methyl group at the third position of the amphetamine structure. This modification alters its pharmacological properties compared to other amphetamines such as [[amphetamine]] and [[methamphetamine]].
+==Pharmacology==
+The pharmacological effects of 3-Methylamphetamine are similar to those of other amphetamines, which typically act as central nervous system stimulants. These effects are primarily due to the compound's ability to increase the release of neurotransmitters such as [[dopamine]], [[norepinephrine]], and [[serotonin]] in the brain.
+===Mechanism of Action===
+-Methylamphetamine acts by promoting the release of monoamines from presynaptic neurons. It is believed to enter the neuron via the dopamine transporter and then induce the release of dopamine into the synaptic cleft. This action is similar to that of other substituted amphetamines.
+==Legal Status==
+The legal status of 3-Methylamphetamine varies by country. In many jurisdictions, it is classified as a controlled substance due to its potential for abuse and lack of accepted medical use. It is important to consult local regulations to determine its legal status in a specific area.
+==Synthesis==
+The synthesis of 3-Methylamphetamine involves the alkylation of amphetamine precursors. This process typically requires specialized knowledge in organic chemistry and access to controlled substances, making it illegal in many regions without proper authorization.
+==Potential Uses==
+While 3-Methylamphetamine has no accepted medical uses, it is sometimes studied in research settings to understand the effects of structural modifications on the activity of amphetamine-like compounds. These studies can provide insights into the development of new therapeutic agents.
+==Related Compounds==
+-Methylamphetamine is related to several other compounds in the amphetamine family, including:
+* [[Amphetamine]]
+* [[Methamphetamine]]
+* [[3,4-Methylenedioxyamphetamine]] (MDA)
+* [[3,4-Methylenedioxymethamphetamine]] (MDMA)
+==Related Pages==
+* [[Amphetamine]]
+* [[Substituted amphetamines]]
+* [[Central nervous system stimulants]]
+{{Amphetamines}}
+[[Category:Substituted amphetamines]]
+[[Category:Stimulants]]