4-Methylamphetamine
4-Methylamphetamine
4-Methylamphetamine (also known as 4-MA) is a stimulant of the amphetamine class. It is a substituted amphetamine that is structurally related to amphetamine and methamphetamine.
Chemical Structure
4-Methylamphetamine is chemically known as 1-(4-methylphenyl)propan-2-amine. It is characterized by the presence of a methyl group attached to the para position of the phenyl ring of the amphetamine backbone. This modification distinguishes it from other amphetamines and contributes to its unique pharmacological properties.
Pharmacology
4-Methylamphetamine acts primarily as a monoamine releasing agent, promoting the release of neurotransmitters such as dopamine, norepinephrine, and serotonin from presynaptic neurons. This action results in increased concentrations of these neurotransmitters in the synaptic cleft, leading to enhanced stimulation of postsynaptic receptors.
Effects
The effects of 4-Methylamphetamine are similar to those of other amphetamines, including increased alertness, energy, and euphoria. However, due to its potent action on serotonin release, it may also produce effects similar to those of MDMA, such as increased empathy and sociability.
Toxicity and Safety
4-Methylamphetamine has been associated with significant neurotoxicity, particularly due to its serotonergic activity. It has been implicated in several cases of serotonin syndrome, a potentially life-threatening condition characterized by excessive serotonergic activity in the central nervous system.
Legal Status
Due to its potential for abuse and adverse health effects, 4-Methylamphetamine is classified as a controlled substance in many jurisdictions. Its legal status varies by country, but it is generally subject to strict regulation.
Related Compounds
Related Pages
Gallery
Structural formula of 4-Methylamphetamine
Ball-and-stick model of 4-Methylamphetamine
Structural formula of 4-Methylamphetamine
Ball-and-stick model of 4-Methylamphetamine
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